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Feb 22, 2026

What Is Protein Structure? Primary, Secondary, Tertiary, Quaternary Explained

The four levels of protein structure and why each matters for function and drug design.

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Feb 20, 2026

How AlphaFold Works — The AI That Solved Protein Folding

How DeepMind's AlphaFold predicts structures using deep learning, MSAs, and attention mechanisms.

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Feb 18, 2026

The Protein Folding Problem — Why It Took 50 Years to Solve

From Anfinsen's experiment to Levinthal's paradox to AlphaFold's breakthrough.

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Feb 16, 2026

Ramachandran Plot Explained — What Phi and Psi Angles Tell You

How backbone dihedral angles define protein conformation and validate structure quality.

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Feb 14, 2026

The 20 Amino Acids — Complete Guide to Properties and Functions

Classification, properties, essential vs non-essential, and roles in structure.

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Feb 12, 2026

PDB File Format Explained — How to Read Protein Structure Files

Understanding ATOM records, coordinates, B-factors, and structure file formats.

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Feb 10, 2026

Protein Domains and Motifs — Structural Building Blocks

How modular domains combine to create functional proteins.

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Feb 8, 2026

Disulfide Bonds in Proteins — Formation, Function, and Importance

How cysteine residues form covalent S-S bridges and why they matter for stability.

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Feb 6, 2026

Protein Structure in Drug Design — From Target to Treatment

How structure prediction accelerates drug discovery and virtual screening.

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Feb 4, 2026

UniProt Database Guide — How to Search and Use Protein Databases

Navigate the world's largest protein database and find UniProt IDs.

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